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This week, an agreement was reached between the Medicines Patent Pool (MPP) and Merck pledges low-cost access to the investigational oral COVID-19 antiviral molnupiravir worldwide, with a particular focus on 105 low and middle-income countries (LMICs).
Jointly developed by Merck and Ridgeback... Read More »
Biotechnology company INOVIO finished enrollment for a West Africa-based Phase 1B clinical trial of INO-4500, its DNA vaccine candidate for Lassa Fever, this week.
A full complement of 220 participants will participate in this first trial for a Lassa fever vaccine in West Africa. The area was... Read More »
Moderna Inc. announced Monday it had a new memorandum of understanding to make up to 110 million doses of the Moderna COVID-19 vaccine available to the African Union.
The company said it is prepared to deliver the first 15 million doses in the fourth quarter of 2021, with 35 million doses... Read More »
With the investment of $26 million announced this week, the Centers for Disease Control and Prevention (CDC) hopes to modernize the science of infectious disease prediction and analytics.
The first investments from CDC’s Center for Forecasting and Outbreak Analytics (CFA) -- which is expected... Read More »
According to top line data from a Phase 2/3 study of Moderna’s COVID-19 vaccine among children ages 6-11, released this week, the company determined that two doses given a month apart produced a strong antibody response -- stronger, even, than those seen in adults.
Conducted in collaboration... Read More »
In recent weeks, the U.S. Department of Health and Human Services (HHS) has invested more than $562 million into U.S. companies to boost domestic manufacturing of COVID-19 tests and supplies.
These funds, pulled from the American Rescue Plan Act, have benefited supplies such as pipette tips,... Read More »
Novartis officials said the company has established an agreement leveraging its manufacturing capacity and capabilities to address the COVID-19 pandemic by expanding Pfizer-BioNTech vaccine support.
The agreement targets the fill and finish of more than 50 million doses in 2021 at the Novartis... Read More »
Lawrence Livermore National Laboratory (LLNL) announced it had joined the international Human Vaccines Project (HVP) Thursday, bringing its expertise and computing resources to the project to aid the development of a universal coronavirus vaccine and to improve understanding of immune response.... Read More »
Recognizing the delays that have plagued low-income countries at nearly every aspect of the COVID-19 pandemic, the Bill & Melinda Gates Foundation announced this week a pledge of up to $120 million to accelerate access to the antiviral drug molnupiravir among low-income nations.
Molnupiravir is... Read More »
Results arrived this week for a Phase 3 trial of Valneva SE’s COVID-19 vaccine candidate, VLA2001, and they revealed neutralizing antibody activity greater than 95 percent, along with broad T-cell responses and significant tolerability.
It was reported that the inactivated, adjuvanted vaccine... Read More »
Lockheed Martin has secured a $9,672,781 Army Project Agreement to continue developing the Terrestrial Layer System (TLS) program for the branch's tactical vehicles.
The action via the Army's Consortium Management Group (CMG)/Consortium for Command, Control, and Communications in Cyberspace (C5)... Read More »
The National Institutes of Health (NIH) Rapid Acceleration of Diagnostics (RADx) initiative split $77.7 million among 12 new contract awards last week for potential, rapid SARS-CoV-2 diagnostic tests.
Part of the RADx Tech program, which gathered a panel of technical, regulatory and business... Read More »
Food and Drug Administration (FDA) officials said the agency will conduct a Nov. 30 meeting via its Antimicrobial Drugs Advisory Committee (AMDAC) to discuss a COVID-19 oral treatment.
The FDA indicated the effort would focus on Merck and Ridgeback’s request for an emergency use authorization... Read More »
Following two successful Phase 3 trials of more than 6,000 patients, the United States Food and Drug Administration (FDA) last week accepted the Regeneron Pharmaceuticals, Inc. anti-COVID-19 cocktail known as REGEN-COV for priority review.
REGEN-COV is a mix of the antibodies casirivimab and... Read More »
The all-star team of government officials, scientists and industry executives who tackled COVID-19 made great strides in the development of an effective vaccine against the novel virus, but that is no guarantee that the United States will be ready for the next pandemic that rears its head, speakers... Read More »
The first participant in a new trial phase recently received a dose of a vaccine candidate against chikungunya disease that is being developed by Emergent BioSolutions Inc.
“Emergent has achieved a major milestone as we begin our phase 3 study for our single-dose chikungunya vaccine... Read More »
Shortly after the terrorist events of Sept. 11, 2001, letters containing deadly anthrax spores arrived at locations across the country, killing five Americans and sickening 17 others. Twenty years after these incidents, considered the worst biological attacks in U.S. history, the federal government... Read More »
The threat detection and security screening technology firm Smiths Detection recently confirmed its BioFlash air sampler detects a series of SARS-CoV-2 variants.
Officials said the detected variants include the Alpha variant, Beta variant, Gamma variant, the Kappa variant and the Delta and Delta... Read More »
In a letter to high-ranking members of the Biden Administration’s COVID-19 response efforts, three Democratic senators and representatives this week urged a cautious review of the United States Health and Human Services (HHS) contract with Moderna, Inc. and called for efforts to expand global... Read More »
Through exercise of an option with Moderna, Inc., Gavi, the Vaccine Alliance will purchase another 176.5 million doses of the company’s COVID-19 vaccine in an effort to help low income countries over the course of the next year, through the COVAX Facility.
With this purchase, COVAX will have... Read More »
According to the latest annual report from the global nonprofit partnership CARB-X, at the close of its fifth fiscal year it has provided as much as $361 million to 92 projects seeking solutions to antibiotic resistant bacteria, gathered new partners under its umbrella and continually grown its... Read More »
Moderna officials said the company is slated to build a messenger RNA (mRNA) facility in Africa, producing up to 500 million vaccine doses annually at the 50 microgram dose level.
“Since Moderna’s founding in 2010, our mission has been to make a transformative impact on human lives through... Read More »
VE303, an oral treatment developed by Vedanta Biosciences for patients at high risk of recurrent C. difficile infections (CDI), will get a Phase 3 clinical evaluation trial, thanks to support from the Biomedical Advanced Research and Development Authority (BARDA).
Support from the U.S. government... Read More »
The World Health Organization (WHO) has recommended the first vaccine to treat malaria in children, a mosquito-borne disease that kills more than 260,000 children under the age of five annually in sub-Saharan Africa, in what public health officials have called a historic development.
“The... Read More »
Although its COVID-19 vaccine was never authorized for use in the United States, AstraZeneca submitted a request with the U.S. Food and Drug Administration (FDA) this week seeking emergency use authorization (EUA) for its long-acting antibody (LAAB) combination for use against symptomatic... Read More »
Ending speculation, Johnson & Johnson (J&J) this week officially submitted data to the United States Food and Drug Administration (FDA) to request emergency use authorization (EUA) for a booster version of its COVID-19 vaccine among patients at least 18 years old.
Recent data showed that the J&J... Read More »
The over-the-counter (OTC) ACON Laboratories Flowflex COVID-19 Home Test has received Food and Drug Administration (FDA) emergency use authorization.
FDA officials said the approval serves as testament to the agency's commitment to increasing the availability of accurate and reliable OTC tests to... Read More »
In a new report issued this week, the Bipartisan Commission on Biodefense warned that the United States needs to protect infrastructure, share and secure information, and maintain public works and services, or risk further devastation from biological threats like COVID-19.
The report was titled... Read More »
Results of an interim analysis for the Phase 3 trial of molnupiravir, an investigational oral antiviral for COVID-19 produced by Merck and Ridgeback Biotherapeutics, showed the drug capable of cutting hospitalization or death risk approximately in half.
For the purposes of the trial, over the... Read More »
Safe and effective: this was the verdict of Phase 3 trial results for Regeneron Pharmaceuticals, Inc.’s REGEN-COV COVID-19 treatment, as published in the New England Journal of Medicine earlier this week.
That trial reportedly met both its primary and secondary endpoints, inducing... Read More »
An ages-old issue may be on the road to modern solutions, thanks to a new collaboration between the Biomedical Advanced Research and Development Authority (BARDA) and Clarivate that will use advanced computer methods to find therapeutics for use on chlorine and sulfur mustard-caused... Read More »
Raytheon Missiles & Defense and Northrop Grumman personnel are touting the successful completion of the first flight test of a scramjet-powered Hypersonic Air-breathing Weapon Concept (HAWC).
The companies are slated to produce a prototype to the Department of Defense for the Defense... Read More »
Earlier this month, the Nuclear Threat Initiative gathered 100 international experts on biosafety for the 2021 Virtual Global Biosecurity Dialogue (GBD), the latest in an annual series of discussions on how best to maintain attention on and advance biosecurity across the world.
COVID-19 loomed... Read More »
The World Health Organization (WHO) approved Regeneron Pharmaceuticals’ drug cocktail of casirivimab and imdevimab for use on COVID-19 patients last week, but that endorsement came with a caveat: it urged lower prices, patent releases and equitable distribution.
The Regeneron antibody... Read More »
At the United States-hosted Global COVID-19 Summit last week, world leaders recommitted to guaranteeing equitable vaccine access for all countries through COVAX, and pledged a mix of funds, doses and supply chain aid to ensure it.
“Science has made huge progress in the fight to save lives,... Read More »
