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Regeneron Pharmaceuticals is making changes to the Phase 3 trial of its Regen-COV treatment for outpatients with COVID-19.
The changes come at the recommendation of the Independent Data Monitoring Committee (IDMC), which said to no longer use a placebo group in the trial. IDMC found clear... Read More »
Pfizer Inc. and BioNTech announced the beginning of an evaluation into the safety and immunogenicity of a third dose of their COVID-19 vaccine last week to study the effects of a booster vaccine against emerging SARS-CoV-2 variants.
This will be offered to up to 144 participants from the phase... Read More »
The first 600,000 doses of the AstraZeneca/Oxford COVID-19 vaccine allocated to the COVAX Facility have been delivered to Ghana, with further deliveries expected to reach Cote d’Ivoire later this week.
It marks the beginning of a global rollout long in the planning and the first COVAX vaccine... Read More »
According to a new study from the National Cancer Institute (NCI), at least a few months of protection may be granted against reinfection to those with SARS-CoV-2.
As part of the National Institutes of Health, NCI worked with healthcare data analytics companies HealthVerity and Aetion, Inc. and... Read More »
The Navy and Air Force have awarded Lockheed Martin a $414 million contract for Long Range Anti-Ship Missile (LRASM) production.
The agreement represents the largest LRASM production pact in the program's history. The combined Lot 4/5 contract continues production of the air-launched variant of... Read More »
A group of lawmakers recently forwarded correspondence to Facebook CEO Mark Zuckerberg, seeking insight regarding the company’s alleged role in knowingly allowing extremist content and groups growth on its platform.
Energy and Commerce Committee Chairman Frank Pallone, Jr. (D-NJ), Oversight... Read More »
A Phase 1B clinical trial of Lassa fever vaccine INO-4500, developed by INOVIO, began dosing its first patient this week in Ghana.
The vaccine is a first on several fronts: the first candidate for Lassa fever to begin human trials and the first to have trials conducted in West Africa, where the... Read More »
A pair of monoclonal antibodies (mAbs) developed by Regeneron have shown promising signs against the coronavirus that causes Middle East respiratory syndrome (MERS) in a phase one clinical trial that marked the first such test conducted on people.
In all, the National Institute of Allergy and... Read More »
Specialty vaccine company Valneva has initiated a Phase 3 study for its single-shot chikungunya vaccine candidate, VLA1553.
VLA1553 is the only chikungunya vaccine candidate in Phase 3 clinical trials. Chikungunya is a mosquito-borne viral disease caused by the chikungunya virus (CHIKV).... Read More »
In an effort to meet global supply demands, Sanofi has agreed to support the manufacturing of a COVID-19 vaccine made by Janssen Pharmaceutical NV and Janssen Pharmaceuticals, Inc., both of which are part of Johnson & Johnson.
The Janssen candidate has been submitted to the U.S. Food and Drug... Read More »
Five COVID-19 vaccine manufacturers assured Congress Tuesday that they are closely watching the emergence of new variants of COVID-19 and are optimistic the two vaccines currently approved in the United States and a third poised for approval will treat those new variants that have emerged in the... Read More »
Lauretta AI, LLC, a start-up based in Arlington, Mass., has secured a Department of Homeland Security (DHS) phase one funding award of $199,950 to aid the development of self-screening Transportation Security Administration (TSA) checkpoints.
The initiative is supported through the DHS's Science... Read More »
Following positive results from preclinical testing at the University of Alabama at Birmingham last year, the Altimmune Inc. COVID-19 vaccine candidate AdCOVID is set to start a phase one clinical trial this week.
Efforts will begin with patient enrollment, now that the U.S. Food and Drug... Read More »
The Biomedical Advanced Research and Development Authority (BARDA) and Luminex Corporation announced a collaboration on advanced development support of a single test to rapidly detect and differentiate between COVID-19, influenza, and respiratory syncytial virus (RSV).
Prevalent pathogens all,... Read More »
Lawrence Livermore National Laboratory (LLNL) researchers are working to determine if, after a terrorist bombing, the bomb maker can be identified by skin proteins left on bomb components.
As a means of conducting the research, personnel from LLNL's Weapons Complex Integration (WCI) and Global... Read More »
In tests conducted by the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), a new screening technology from Smiths Detection broke new ground in efforts to find and contain COVID-19: the capability to detect the virus SARS-CoV-2 in the air.
The BioFlesh Biological... Read More »
Building off a 2020 research and development agreement for coronavirus therapies, GlaxoSmithKline plc (GSK) and Vir Biotechnology, Inc. announced a binding agreement this week to expand that collaboration into new therapies for flu and other respiratory viruses.
The pair will work together on... Read More »
The U.S. Department of Defense awarded a $1.4 million grant to scientists at West Virginia University (WVU) to develop therapeutics to treat infections prone to antibiotic resistance.
Mariette Barbier of the WVU School of Medicine will lead the research effort. Barbier and her team will present... Read More »
Army officials said Lockheed Martin is slated to begin supporting formal integration and testing of the branch's combat vehicle protection system to keep soldiers safer and more secure from threats.
Lockheed Martin would provide its Modular Active Protection System (MAPS) base kit, which... Read More »
Following the World Health Organization (WHO) emergency use listing of the AstraZeneca/University of Oxford COVID-19 vaccine this week, the COVAX initiative announced it intends the bulk of the first deliveries to occur in March.
COVAX is finalizing the first and second quarter allocations of... Read More »
A new report from the Johns Hopkins Center for Health Security addresses the status of SARS-CoV-2 surveillance, sequencing, and the three emerging variant strains, establishing four policy recommendations to identify and manage them.
“Staying Ahead of the Variants: Policy Recommendations to... Read More »
A joint document recently released by the Nuclear Innovation Alliance (NIA) and Partnership for Global Security (PGS) defines a comprehensive domestic strategy to advance nuclear power development.
“Clean energy technologies, including advanced nuclear energy, are essential to meet mid-century... Read More »
Another four COVID-19 therapeutics for those with mild to moderate symptoms moved further up the pipeline this week, with the announcement of enrollment for Phase 2/3 testing in the National Institute of Allergy and Infectious Diseases (NIAID) ACTIV-2 trial.
ACTIV, or the Accelerating COVID-19... Read More »
The World Health Organization (WHO) formally approved emergency authorization for AstraZeneca’s COVID-19 vaccine, allowing two versions of it to be distributed through the global COVAX program.
AstraZeneca-SKBio is producing the two vaccines in the Republic of Korea and the Serum Institute of... Read More »
BAE Systems has been awarded a $184 million contract option via the Marine Corps, covering production, fielding, and support costs for the Amphibious Combat Vehicles personnel carrier (ACV-P) variant.
The firm was awarded the initial full-rate production contract option in December for the... Read More »
The Johns Hopkins Center for Health Security introduced a new website last week known as the COVID-19 Testing Toolkit to provide essential information on available tests, testing services, how they work, and how accurate they are for any interested organizations.
“For a lot of organizations,... Read More »
Emergent BioSolutions Inc. on Friday announced a new contract development and manufacturing company (CDMO) agreement with Canadian-based Providence Therapeutics, which is producing a messenger RNA (mRNA) vaccine similar to the Moderna Inc. and Pfizer-BioNTech coronavirus shots already being... Read More »
The Defense Advanced Research Project Agency's (DARPA) Tactical Technology Office (TTO) has awarded Northrop Grumman Corporation a contract to develop an advanced technology weapon concept.
The effort would increase the engagement range and weapon effectiveness of domestic forces against... Read More »
Through a letter of intent released this week, AstraZeneca and IDT Biologika pledged to increase COVID-19 vaccine manufacturing in Europe and guarantee long-term supply capacity.
While the details are still up in the air, both companies also intend to invest in drug substance capacity.... Read More »
The U.S. Army announced that it will continue its relationship with Skydio, the leading U.S. drone manufacturer.
Specifically, the Army will continue with the Skydio X2D SRR system to complete the remaining integration and documentation requirements within the Other Transaction Agreement... Read More »
AppCensus, a start-up from El Cerrito, Calif., won a $198,600 award from the Department of Homeland Security (DHS) Science and Technology Directorate (S&T) to develop testing and validation services for digital contact tracing applications.
The phase 1 award was made under S&T’s... Read More »
Lockheed Martin officials said the aerospace company has contracted with ABL Space Systems to supply a rocket and associated launch services for Lockheed Martin's first UK vertical satellite launch.
The UK Pathfinder Launch is slated to be the first vertical small satellite launch from UK soil... Read More »
Following preliminary data that showed the AstraZeneca/Oxford COVID-19 vaccine to have minimal effect in preventing mild to moderate cases of a South African variant, the global COVAX initiative has nevertheless stressed the need to assess its efficacy against more severe illness.
Preliminary... Read More »
The National Institutes of Allergy and Infectious Diseases (NIAID) this week began enrolling participants for an international phase three clinical trial of AZD7442, an antibody combination developed by AstraZeneca to treat those hospitalized with COVID-19.
The trial is part of ACTIV-3, a... Read More »
Emergent BioSolutions Inc. on Monday hosted Maryland Gov. Larry Hogan at the multinational biopharmaceutical company’s East Baltimore, Md., Bayview facility where the Johnson & Johnson COVID-19 vaccine candidate is being manufactured.
Emergent’s Bayview facility, which is designated by... Read More »
