Research
According to preclinical data produced by Soligenix, Inc. this week, positive, effective results have been demonstrated by multiple filovirus vaccine candidates.
In collaboration with the University of Hawaiʻi at Mānoa, Soligenix’s vaccines proved capable against three potentially deadly... Read More »
Utilizing initial funding from the American Rescue Plan, the U.S. Centers for Disease Control and Prevention (CDC) unveiled plans this week for a new Center for Forecasting and Outbreak Analytics, focused on forecasts of disease outbreaks and analytics for public health.
The new center will be... Read More »
The U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T) recently composed an Environmental Assessment draft regarding a New York City aerosol particle behavior study.
“This study is part of the Department’s ongoing commitment to public safety against the... Read More »
Federal Emergency Management Agency (FEMA) announced this week that it has launched the National Risk Index, designed to provide guidance regarding nationwide natural hazard risks.
Authorities indicated the resource also seeks to inform and educate communities as a means of helping to reduce the... Read More »
The National Institutes of Health (NIH) announced this week that it will award approximately $53 million in annual funding across the next five years to 10 research organizations currently pursuing HIV cure research.
“June marked the 40th anniversary of the first reported U.S. cases of what... Read More »
As part of a new agreement with Gritstone bio, Inc., the Coalition for Epidemic Preparedness Innovations (CEPI) will provide up to $20.6 million to support the development of a new, self-amplifying mRNA vaccine candidate for the growing number of COVID-19 variants.
These funds will cover a... Read More »
A preclinical study conducted on non-human primates and published this week showed potential in a second-generation mRNA COVID-19 vaccine candidate, CV2CoV, created by the joint efforts of biopharmaceutical companies CureVac N.V. and GSK.
Among cynomolgus macaques, the new candidate -- an... Read More »
With diagnostic testing as important as ever in the battle to contain COVID-19, researchers from various institutions under the umbrella of the National Institutes of Health (NIH) have banded together to create a new sample preparation method for detecting SARS-CoV-2.
The collaboration has... Read More »
The specialty vaccine firm Valneva SE has initiated a Phase 3 trial for its COVID-19 vaccine candidate, VLA2001.
VLA2001-304 seeks to generate data in the elderly and is designed to potentially enable variant-bridging through immune-comparability. Study data is slated to complement ongoing... Read More »
The Government Accountability Office (GAO) has issued seven recommendations to the National Nuclear Security Administration (NSSA) regarding lithium activities.
The analysis and recommendations stem from NSSA facilities deteriorating and the agency proposing a new facility to meet lithium... Read More »
According to a new manuscript published in Science last week, the majority of people given Moderna Inc.’s COVID-19 vaccine maintained antibodies not just against SARS-CoV-2, but against many of its variants of concern, for six months after a second dose.
The two-dose vaccine has been... Read More »
The Defense Advanced Research Projects Agency recently selected three teams to support the Harnessing Enzymatic Activity for Lifesaving Remedies (HEALR) program.
The HEALR program, which bolsters chemical biology, medicinal chemistry, and microbiology expertise to transform the field of... Read More »
Groups of medical experts this week proposed a standardized definition for defining and evaluating placental SARS-CoV-2 infections to optimize both clinical care and new research, as well as the pursuit of COVID-19 vaccinations for pregnant individuals.
The first came from a panel of experts... Read More »
Regulatory approval was granted for two new clinical trials of INO-4800 in China this week, allowing its creator INOVIO and its partners Advaccine Biopharmaceuticals Suzhou Co. Ltd. and Sinovac Biotechnology to investigate the safety, tolerability, and immunogenicity of different... Read More »
A new partnership announced last week between Integrum Scientific and the Coalition for Epidemic Preparedness Innovations (CEPI) will advance progress toward a Rift Valley fever (RVF) vaccine by developing an international antibody standard and validation of new assays.
From now until September... Read More »
BARDA’s Division of Research Innovation and Ventures (DRIVe) announced Thursday that it will partner with US Biologic Inc. to develop an oral vaccine for two strains of the influenza virus.
Part of BARDA DRIVe’s Beyond the Needle program, the partnership’s goal is to make vaccines and... Read More »
A Phase Three trial of Valneva SE’s chikungunya vaccine candidate, VLA1553, met with major success, according to topline results released last week that showed it induced protective neutralizing antibody titers in 98.5 percent of subjects after a single vaccination.
The trial involved 4,115... Read More »
Biotechnology company INOVIO dosed its first participant in a Phase 2 trial of a DNA vaccine for Middle East Respiratory Syndrome (MERS).
MERS, another coronavirus disease, is far deadlier than COVID-19, with a kill rate of approximately 34 percent. Fortunately, though, its transmission rate has... Read More »
A cocktail of casirivimab and imdevimab known as REGEN-COV, produced by Regeneron Pharmaceuticals, Inc., cut the risk of symptomatic infections by 81 percent in a Phase 3 trial of more than 1,500 people, according to a new publication in the New England Journal of Medicine.
Even better,... Read More »
A new report released this week by United States Sens. Rob Portman (R-OH) and Gary Peters (D-MI) revealed glaring cybersecurity failures at eight federal agencies over the past decade, along with the inability of seven of them to comply with basic cybersecurity requirements.
The Federal... Read More »
The U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T) released its Artificial Intelligence & Machine Learning (AI/ML) Strategic Plan on Friday.
The proposed plan will incorporate the technological advancements in AI/ML to enhance the efficiency and... Read More »
Faced with a disease that tends to hit suddenly, erratically, and with extremely lethal effects, the Coalition for Epidemic Preparedness Innovations (CEPI) announced last week that it will provide up to $188,000 to support Universiti Malaya (UM) research into the Nipah virus.
UM, based in... Read More »
This year marks the fifth anniversary of the founding of Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X), a global non-profit partnership dedicated to funding and supporting the development of new products to counter antibiotic-resistant bacteria.
According to... Read More »
State funding for public health departments has dropped by 16 percent since 2010, and these same departments have lost a quarter of their workforce in the last decade.
How can the United States adequately prepare for the next pandemic when the public health infrastructure is woefully... Read More »
In a first for virus detection, the company Opteev this week launched a plug-in airborne virus detector known as ViraWarn to scan for COVID-19, flu, and other virus particles in the air indoors and then warn those who might be affected.
Meant as prevention rather than confirmation of infection,... Read More »
What is already the largest ever Lassa fever assessment study will expand to reach Benin, Guinea, Liberia, and Sierra Leone, thanks to an additional $10.3 million from the Coalition for Epidemic Preparedness Innovation (CEPI).
“There have been a number of positive developments in the Lassa... Read More »
A new, Battelle-developed system known as TechAware Search Continuous Automated Scanning for Technology Transformation (CASTT) proposes to help identify epidemic threats through a mix of text data analysis, behavioral change prediction, and creation of a graph neural network.
The project is... Read More »
With the COVID-19 pandemic entering a new phase, the Biomedical Advanced Research and Development Authority (BARDA) continues to emphasize testing in addition to the growing number of vaccines, and as such, has entered a new agreement with Cepheid, Inc. to develop two additional... Read More »
For the launch of the third series of the Virtual Whole-of-Government Research and Development (R&D) Showcase this week, the Department of Homeland Security (DHS) Science and Technology Directorate (S&T) is looking to address upcoming scientific fields changing the world and how it handles... Read More »
Recognizing that many data sets are needed to tell the full story of the COVID-19 pandemic and understand if herd immunity can be achieved, two scientists from the University of Washington have created a statistical model of key COVID-19 data to model the disease’s true prevalence in the United... Read More »
A single dose of Vaxzevria was shown to be 82 percent effective against cases of severe disease, hospitalization, or death caused by Beta/Gamma variant of SARS-CoV-2, according to pre-print data from the Canadian Immunization Research Network (CIRN).
Vaxzevria is another two-dose vaccine.... Read More »
The Defense Critical Supply Chain Task Force recently released final report findings and recommendations regarding threats and vulnerabilities.
“Throughout the pandemic, U.S. adversaries like China weaponized supply chain vulnerabilities in a way that threatened Americans’ health and... Read More »
The U.S. Department of Homeland Security (DHS) recently awarded $2 million to two small businesses to develop advanced, affordable, and handheld detection imaging technology to screen passengers.
Those chosen included Spectral Labs Inc., of San Diego, Calif., and TeraMetrix LLC, of Ann Arbor,... Read More »
Continuing to flesh out medical countermeasure options for the ongoing threat of COVID-19, the Coalition for Epidemic Preparedness Innovations (CEPI) announced this week that it will provide $13.1 million to Shanghai Zerun Biotechnology Co., Ltd. for clinical trials and scale-up support of vaccine... Read More »
The U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T) recently issued a request for information (RFI) regarding commercial Blast Resistant Trash Receptacles (BRTRs).
“Trash receptacles appear in most public spaces as essential but ordinary objects,” National... Read More »
