Emerging Infectious Diseases
The Biomedical Advanced Research and Development Authority (BARDA) initiated a partnership with digital health developer Empatica last week that focuses on developing a wearable system and algorithm that can detect early signs of COVID-19 infection in individuals.
That system, known as Aura,... Read More »
Researchers at the Department of Homeland Security (DHS) Science and Technology Directorate (S&T) have developed a way for people to decontaminate personal protective equipment (PPE) at home.
DHS’s S&T researchers have found that programmable multicookers can be used to decontaminate masks,... Read More »
Department of Health and Human Services (HHS) and Department of Defense (DOD) officials said the agencies have partnered to expedite vial manufacturing capacity amid the COVID-19 pandemic.
Through Operation Warp Speed, the Biomedical Advanced Research and Development Authority (BARDA), under the... Read More »
The lack of a cohesive national plan for dealing with COVID-19 was once more brought to the fore last week with the release of a report from the Johns Hopkins Center for Health Security, which laid out a series of recommendations surrounding antibody studies.
These antibody studies --... Read More »
Emergent BioSolutions revealed this week plans to expand its viral vector and gene therapy capabilities.
The company announced it will invest $75 million in its Canton, Mass., facility, which is focused on the contract development and manufacturing (CDMO) of drug substances for live viral... Read More »
The Senate voted to support GAVI, the Vaccine Alliance, this week through a resolution introduced by U.S. Sens. Marco Rubio (R-FL) and Time Kaine (D-VA).
The resolution commends and reaffirms support for GAVI. It also puts the nation’s money where its mouth is, so to speak, pledging U.S.... Read More »
A pair of automated antibody tests created by Ortho Clinical Diagnostics to track down COVID-19 will be further developed thanks to a new partnership between the company and the Biomedical Advanced Research and Development Authority (BARDA).
The tests are known as VITROS Anti-SARS-COV-2 Total... Read More »
The U.S. government has reached agreements with both Canada and Mexico to limit all non-essential travel across borders to limit the further spread of coronavirus.
The Department of Homeland Security is a crucial part of this North American approach to stop the spread of the virus, as will the... Read More »
The Bipartisan Commission on Biodefense is calling for a renewed commitment to fighting COVID-19, urging Americans to protect each other.
“We formed the Bipartisan Commission on Biodefense six years ago because we suspected and subsequently confirmed that our Nation was vulnerable to biological... Read More »
In exchange for rapidly testing drugs for potential repurposing as COVID-19 treatments, University of Maryland School of Medicine (UMSOM) researchers will receive up to $3.6 million from the Defense Advanced Research Projects Agency (DARPA) over the next year.
All of the drugs to be tested are... Read More »
Results from a University of Oxford study found that the low-cost, low-dose steroid dexamethasone was revealed this week to have reduced COVID-19 deaths by up to one third in patients hospitalized with the disease.
This is the first time a therapy has demonstrated any ability to improve survival... Read More »
Pharmaceutical company SIGA Technologies, Inc. gained a boost to its work toward a label expansion for TPOXX, an antiviral drug for treating smallpox caused by variola virus, thanks to an increase in funding from the U.S. Department of Defense (DoD) this week.
With the addition, DoD is now... Read More »
Biotechnology company Regeneron has begun clinical trials of its REGN-COV2 cocktail, a two-antibody therapeutic for COVID-19, with recent funding from the Biomedical Advanced Research and Development Authority (BARDA).
The therapeutic proposes to inhibit SARS-CoV-2, the virus that causes... Read More »
Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson, has accelerated the initiation of the Phase 1/2a first-in-human clinical trial of its investigational COVID-19 vaccine.
The trial is expected to commence in the second half of July, moved up from its initial September time frame.... Read More »
Under the terms of a new contract, Bavarian Nordic will manufacture and deliver additional cases of the MVA-BN Filo vaccine in bulk to Janssen Vaccines & Prevention B.V., building its supply of Ebola vaccines.
The deal, valued $13.9 million, will kick off this year and build on the more than 2... Read More »
Showcasing how much more has been learned about COVID-19 since its discovery, the Department of Homeland Security Science and Technology Directorate (S&T) added an online calculator last week that estimates the natural decay of SARS-CoV-2 in the air.
SARS-CoV-2, which causes COVID-19, is... Read More »
The Director General of the International Atomic Energy Agency (IAEA), Rafael Mariano Grossi, introduced a new initiative to enhance global preparedness for future pandemics like COVID-19.
The Zoonotic Disease Integrated Action (ZODIAC) seeks to establish a global network to help national... Read More »
The Defense Advanced Research Projects Agency (DARPA) is working to develop new treatments to combat microbial infections.
Through its Harnessing Enzymatic Activity for Lifesaving Remedies (HEALR) program, DARPA seeks to use new tools and strategies to treat microbial infections. Specifically,... Read More »
Arguing the potential benefits no longer outweigh the health risks involved, the U.S. Food and Drug Administration (FDA) on Monday revoked its Emergency Use Authorization for hydroxychloroquine and chloroquine to be used as a treatment for patients with COVID-19.
“We’ve made clear throughout... Read More »
The Biomedical Advanced Research and Development Authority (BARDA) and Snapdragon Chemistry are teaming up to develop a continuous manufacturing platform to produce a specific raw material for COVID-19 vaccines.
They are developing ribonucleotide triphosphates (NTPs), a critical raw material for... Read More »
Regeneron Pharmaceuticals initiated the first clinical trial of REGN-COV2, an antibody cocktail for the prevention and treatment of COVID-19.
The REGN-COV2 clinical program will consist of four separate study populations, including hospitalized COVID-19 patients, non-hospitalized symptomatic... Read More »
Health experts maintain the federal government needs to craft a plan to distribute COVID-19 vaccines in Black and Latino that have borne the brunt of the pandemic nationwide.
“They are going to have to make sure we have a sound distribution plan to make sure that we don’t repeat the mistakes... Read More »
Testing of Moderna’s mRNA-1273 COVID-19 vaccine candidate moved forward this week, with the announcement that arrangements are being made to study 30,000 subjects as part of a phase 3 study in July and manufacturing set to reach as high as 1 billion 100 microgram doses per year in... Read More »
Emergent BioSolutions Inc. announced Thursday it signed an agreement to provide its contract development and manufacturing (CDMO) services to support AstraZeneca's COVID-19 vaccine candidate in the United States.
The agreement, valued at approximately $87 million, gives Emergent stateside... Read More »
The Department of Defense (DoD) has initiated five Defense Production Act Title 3 officials said would aid in sustaining defense-critical workforce capabilities amid the COVID-19 pandemic.
The $135 million action assists in retaining body armor, aircraft manufacturing, and shipbuilding... Read More »
Another SARS-CoV-2 laboratory diagnostic has caught the attention of the Biomedical Advanced Research and Development Authority (BARDA), which is teaming up with OraSure Technology, Inc. to get it United States Food and Drug Administration (FDA) Emergency Use Authorization (EUA).
This test,... Read More »
For three years, the Biomedical Advanced Research and Development Authority (BARDA) has supported the development of Chembio Diagnostics’ DPP Zika IgM System diagnostic system, and now, the result has been approved for marketing by the U.S. Food and Drug Administration.
The test detects... Read More »
The U.S. Food and Drug Administration granted an emergency use authorization to Illumina for the first COVID-19 diagnostic test utilizing next generation sequence technology.
The Illumina COVIDSeq Test is for the qualitative detection of SARS-CoV-2 RNA from respiratory specimens collected from... Read More »
U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T) inventors John Neilan and Michael Puckette have come up with a breakthrough to treat foot-and-mouth disease (FMD) in livestock.
FMD is a disease that is extremely contagious and afflicts animals with cloven... Read More »
The Biomedical Advanced Research and Development Authority (BARDA) and the Defense Advanced Research Projects Agency (DARPA) have reached an interagency agreement with AstraZeneca to support phase 1 clinical development of a monoclonal antibody combination therapy for use against COVID-19.
This... Read More »
U.S. Reps. Brian Fitzpatrick (R-PA) and Conor Lamb (D-PA) introduced legislation that would require foreign nations to implement systems for reporting and monitoring outbreaks of novel diseases.
In addition, the Never Again International Outbreak Prevention Act (H.R. 7132) would sanction bad... Read More »
A highly anticipated University of Minnesota study examining the use of hydroxychloroquine among young health care workers found the drug does not prevent symptoms of COVID-19.
The randomized trial primarily examined the use of the drug on 821 young participants with a median age of 40, who... Read More »
The University of Queensland (UQ) has partnered up with CSL and the Coalition for Epidemic Preparedness Innovations (CEPI) to accelerate development, manufacturing, and distribution of a COVID-19 vaccine candidate its researchers pioneered earlier this year.
In an agreement formalized this week,... Read More »
Results are in from the phase 1 human trial of the Bavarian Nordic A/S vaccine candidate MVA-BN WEV, a prophylactic meant for use against three equine encephalitis viruses, and the data paints the picture of a well-tolerated vaccine capable of spurring immune responses.
The vaccine is meant to... Read More »
FLIR Systems officials said the company has developed software for its T-Series, Exx-Series, and A-Series thermal imaging cameras to perform COVID-19 elevated skin temperature screenings in high-traffic areas.
Officials said the process via FLIR Screen-EST can be conducted in two seconds or less... Read More »
