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Biotechnology company INOVIO dosed its first participant in a Phase 2 trial of a DNA vaccine for Middle East Respiratory Syndrome (MERS).
MERS, another coronavirus disease, is far deadlier than COVID-19, with a kill rate of approximately 34 percent. Fortunately, though, its transmission rate has... Read More »
A cocktail of casirivimab and imdevimab known as REGEN-COV, produced by Regeneron Pharmaceuticals, Inc., cut the risk of symptomatic infections by 81 percent in a Phase 3 trial of more than 1,500 people, according to a new publication in the New England Journal of Medicine.
Even better,... Read More »
The U.S. Department of Homeland Security (DHS) recently announced that it awarded Small Business Innovation Research (SBIR) grants to two companies.
The companies will use the money to develop an in-building coverage analysis system (ICAS) that will use existing first responder radio and... Read More »
Faced with a disease that tends to hit suddenly, erratically, and with extremely lethal effects, the Coalition for Epidemic Preparedness Innovations (CEPI) announced last week that it will provide up to $188,000 to support Universiti Malaya (UM) research into the Nipah virus.
UM, based in... Read More »
This year marks the fifth anniversary of the founding of Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X), a global non-profit partnership dedicated to funding and supporting the development of new products to counter antibiotic-resistant bacteria.
According to... Read More »
The Food and Drug Administration (FDA) is permitting Emergent BioSolutions Inc. to resume manufacturing the Johnson & Johnson COVID-19 Janssen vaccine at its Bayview facility in Baltimore, according to the multinational biopharmaceutical company.
“We are proud to be resuming production of... Read More »
State funding for public health departments has dropped by 16 percent since 2010, and these same departments have lost a quarter of their workforce in the last decade.
How can the United States adequately prepare for the next pandemic when the public health infrastructure is woefully... Read More »
In a first for virus detection, the company Opteev this week launched a plug-in airborne virus detector known as ViraWarn to scan for COVID-19, flu, and other virus particles in the air indoors and then warn those who might be affected.
Meant as prevention rather than confirmation of infection,... Read More »
A new, Battelle-developed system known as TechAware Search Continuous Automated Scanning for Technology Transformation (CASTT) proposes to help identify epidemic threats through a mix of text data analysis, behavioral change prediction, and creation of a graph neural network.
The project is... Read More »
With the COVID-19 pandemic entering a new phase, the Biomedical Advanced Research and Development Authority (BARDA) continues to emphasize testing in addition to the growing number of vaccines, and as such, has entered a new agreement with Cepheid, Inc. to develop two additional... Read More »
Recognizing that many data sets are needed to tell the full story of the COVID-19 pandemic and understand if herd immunity can be achieved, two scientists from the University of Washington have created a statistical model of key COVID-19 data to model the disease’s true prevalence in the United... Read More »
A single dose of Vaxzevria was shown to be 82 percent effective against cases of severe disease, hospitalization, or death caused by Beta/Gamma variant of SARS-CoV-2, according to pre-print data from the Canadian Immunization Research Network (CIRN).
Vaxzevria is another two-dose vaccine.... Read More »
Continuing to flesh out medical countermeasure options for the ongoing threat of COVID-19, the Coalition for Epidemic Preparedness Innovations (CEPI) announced this week that it will provide $13.1 million to Shanghai Zerun Biotechnology Co., Ltd. for clinical trials and scale-up support of vaccine... Read More »
The U.S. Department of Homeland Security (DHS) Science and Technology Directorate (S&T) recently issued a request for information (RFI) regarding commercial Blast Resistant Trash Receptacles (BRTRs).
“Trash receptacles appear in most public spaces as essential but ordinary objects,” National... Read More »
All 625 slots of a randomized Phase 2 trial of the joint-Valneva SE and Pfizer Inc. Lyme disease vaccine candidate VLA15-221 have been filled with participants, finishing the recruitment phase of the trial.
The trial is focused on participants between 5 to 65 years old. They will receive doses... Read More »
A phase 2/3 study that put oral opaganib to 475 patients hospitalized with severe COVID-19 affiliated pneumonia concluded this week, and its creator, RedHill Biopharma Ltd., said that top-line results are expected to follow in a matter of weeks.
"Emerging data is showing that variants are... Read More »
Partners in COVAX, a global collaborative effort to accelerate development, manufacturing and equitable access to COVID-19 vaccines, launched the COVAX Marketplace last week to match buyers with suppliers through a secure new platform and overcome short-term bottlenecks.
The Marketplace is a... Read More »
A new, joint effort between the Department of Homeland Security’s (DHS’s) Science and Technology Directorate (S&T) and the nonprofit Beacon NGO will seek to build upon S&T’s Next-Generation Incident Command System (NICS) and pitch it to a larger emergency response community.
To achieve... Read More »
The Department of Homeland Security (DHS) Science and Technology Directorate (S&T) announced this week that it has partnered with several entities to evaluate the use of autonomous surface and underwater ocean surveillance technology.
The agency has teamed up with the University of Southern... Read More »
A total of $153 million was split between two projects under the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIMBL) this week, as awarded by the United States Department of Commerce’s National Institute of Standards and Technology (NIST).
“I am so pleased that... Read More »
Noting that with advances in biological sciences comes the potential for abuse, the Johns Hopkins Center for Health Security applauded the InterAcademy Partnership this week for endorsing new Guidelines for Codes of Conduct for Scientists produced by Tianjin Biosecurity.
These guidelines,... Read More »
Northrop Grumman Corporation announced Tuesday that its Hypersonics Center of Excellence is currently under construction and once completed, would support the nation's military and allies in combating threats.
The 60,000-square-foot site in Elkton, Md., would offer production for hypersonic... Read More »
Approximately $398 million was issued by the U.S. Department of Health and Human Services (HHS) this week through the Health Resources and Services Administration (HRSA) as a means of helping 1,540 small rural hospitals address COVID-19 testing and mitigation.
“Our state-based SHIP grantees... Read More »
Teams from the Bechtel Corporation at the Blue Grass Chemical Agent-Destruction Pilot Plant (BGCAPP) near Richmond, Ky., have begun purging another batch of chemical weapons, continuing a campaign that intends to destroy nearly 18,000 rockets bearing the VX nerve agent.
The latest round begins... Read More »
The National Emergency Number Association (NENA) announced this week the organization's approval of a new version of its Next Generation 9-1-1 standard.
The action would aid the process of accelerating the transition to faster emergency response, detailing NG9-1-1 infrastructure updates that... Read More »
With a pair of new advance purchase agreements arranged this week, Gavi, the Vaccine Alliance, intends to add two inactivated virus vaccines for COVID-19 to its stores for COVAX -- one from Sinopharm and one from Sinovac.
Sinopharm’s offering is BBIBP-CorV, which will become available this... Read More »
The Bipartisan Commission on Biodefense urged Congress to take action to protect the country’s critical infrastructure from biological threats on Wednesday.
In two recent reports, The Apollo Program for Biodefense: Winning the Race Against Biological Threats, and Biodefense in Crisis:... Read More »
BAE Systems has secured an Army contract worth up to $600 million for sustainment and support for the U.S. Army's Armored Multi-Purpose Vehicle (AMPV) over the next five years.
“The AMPV family of vehicles will bring unmatched capability to the battlefield and has demonstrated outstanding... Read More »
The first healthy adult participants of the Phase 1/2 randomized and observer-blinded test of Moderna’s new quadrivalent seasonal flu vaccine were dosed last week, officially beginning a trial much desired by global health experts.
The World Health Organization (WHO) has a list of targets for... Read More »
Questions were spurred last week with news from Pfizer and BioNTech that progress was being made on a COVID-19 vaccine booster the companies indicated would likely be needed in the future -- a stance promptly contradicted by the U.S. Food and Drug Administration (FDA) and the Centers for Disease... Read More »
While the efficacy of many COVID-19 vaccines has largely been established, more specific questions remain, such as their effectiveness on the immunosuppressed and transplant patients -- a fact that has prompted a new study, led by the Oslo University Hospital and funded by a series of national and... Read More »
LightDeck Diagnostics, which produces both SARS-CoV-2 Ultra-Rapid Antigen and COVID-19 Total Antibody Tests, was awarded a $35.1 million contract from the U.S. Department of Defense (DoD) last week to increase production capacity for these speedy diagnostics.
Both tests are point-of-care tests... Read More »
A recent study by scientists at the National Institutes of Health suggests that one in every four COVID-19 deaths in the United States may be attributed to hospitals strained by surging caseloads.
Published in the Annals of Internal Medicine, the study looked at data from 150,000 COVID-19... Read More »
Huntington Ingalls Industries announced this week that it entered a definitive agreement to purchase Aion Science and Technology from Veritas Capital for $1.65 billion in cash, providing further inroads for Huntington into the global defense marketplace.
As a result of the agreement, Alion will... Read More »
A nationwide study from the University of Utah found that those who receive mRNA COVID-19 vaccines are 91 percent less likely to develop the disease than those who are unvaccinated.
This news came from the RECOVER (Research on the Epidemiology of SARS-CoV-2 in Essential Response Personnel)... Read More »
